初心者向け【ブック メーカー 始め 方】徹底解説 2024年

入学希望の方一般・社会人の方研究者の方同窓生の方在学生の方教職員の方 日本語 (Japanese) Graduate School of Life Sciences, Tohoku University Access sitemap Link Tohoku University HOMEAbout UsAbout UsMessage from the DeanOrganizationMovieResearchLaboratories Department of Integrative Life Sciences Department of Ecological Developmental Adaptability Life Sciences Department of Molecular and Chemical Life SciencesResearchAwardEducationDegree ProgramsCourseSyllabusScheduleStudent LifeAdmissionAdmission InformationApplicationExamination Schedule and Application GuidelinesInformation Session(2024)Admission and Tuition FeesAdmission PolicyVoices from Graduates and Current StudentsAdmissions Q&AInquiries about Entrance ExaminationsFinancial SupportFor StudentsGraduate School&＃039;s Message Board for Students Information about Completion and Advancement to the Doctoral Course ProceduresCertificatesAbout Issuance of Various CertificatesNotice Regarding the Suspension of Operation of the Automatic Certificate Issuing MachinesLeave of absence/withdrawal from universityCampus Life, Various consultation servicesContactAccessLinkSitemapInformationAdmissionResearchAwardSeminarJobNewsAnnouncementOther MENU HOMEAbout UsAbout UsMessage from the DeanOrganizationMovieResearchLaboratoriesResearchAwardEducationDegree ProgramsCourseSyllabusScheduleStudent LifeAdmissionAdmission InformationApplicationExamination Schedule and Application GuidelinesInformation Session(2024)Admission and Tuition FeesAdmission PolicyVoices from Graduates and Current StudentsAdmissions Q&AInquiries about Entrance ExaminationsFinancial SupportFor StudentsGraduate School&＃039;s Message Board for Students Information about Completion and Advancement to the Doctoral Course ProceduresCertificatesLeave of absence/withdrawal from universityCampus Life, Various consultation servicesContactAccessLinkSitemapInformationAdmissionResearchAwardSeminarJobNewsAnnouncementOther 日本語 (Japanese) CLOSE Graduate School of Life Sciences, Tohoku University. Field Integrative Life Sciences :Cellular Network Research HOME Research Researcher JAPANESE Professor FUKUDA Mitsunori Campus Aobayama campus Laboratory Membrane Trafficking Mechanisms Tel +81-22-795-7731 E-mail nori＠tohoku.ac.jp Website http://www.biology.tohoku.ac.jp/lab-www/fukuda_lab/home-ja.html http://www.ac.cyberhome.ne.jp/~fukuda/top_page.htm ResearcherID: I-1511-2015 Google Scholar https://scholar.google.co.jp/citations?user=O5d7nY8AAAAJ&hl=ja&oi=ao My hobbies are nature watching and sports, but professionally I am advancing research involving membrane trafficking. I am searching for ambitious students looking to be future researchers. Don’t hesitate to get in touch with me! Career 1990 Graduated, Biological Institute, Faculty of Science, Tohoku University 1992 Completed master’s program, Department of Biology, Graduate School of Science, Tohoku University 1996 Completed doctoral program, Graduate School of Medicine, The University of Tokyo   Research Fellowship for Young Scientists, JSPS 1998 Research Scientist, Laboratory for Developmental Neurobiology, RIKEN Brain Science Institute 2002 Unit Leader, Fukuda Initiative Research Unit, RIKEN 2006 Professor, Graduate School of Life Sciences, Tohoku University Selected Publications Nakashima, S., Matsui, T. and Fukuda, M. (2023) Vps9d1 regulates tubular endosome formation through specific activation of Rab22A. J. Cell Sci. 136, jcs260522 Hiragi, S., Matsui, T., Sakamaki, Y. and Fukuda, M. (2022) TBC1D18 is a Rab5-GAP that coordinates endosome maturation together with Mon1. J. Cell Biol. 221, e202201114 Matsui, T., Sakamaki, Y., Nakashima, S. and Fukuda, M. (2022) Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells. Cell Rep. 39, 110875 Maruta, Y. and Fukuda, M. (2022) Large Rab GTPase Rab44 regulates microtubule-dependent retrograde melanosome transport in melanocytes. J. Biol. Chem. 298, 102508 Hatoyama, Y., Homma, Y., Hiragi, S. and Fukuda, M. (2021) Establishment and analysis of conditional Rab1- and Rab5-knockout cells using the auxin-inducible degron system. J. Cell Sci. 134, jcs259184 Matsui, T., Osaki, F., Hiragi, S., Sakamaki, Y. and Fukuda, M. (2021) ALIX and ceramide differentially control polarized small extracellular vesicle release from epithelial cells. EMBO Rep. 22, e51475 Osaki, F., Matsui, T., Hiragi, S., Homma, Y. and Fukuda, M. (2021) RBD11, a bioengineered Rab11-binding module for visualizing and analyzing endogenous Rab11. J. Cell Sci. 134, jcs257311 Oguchi, M. E., Okuyama, K., Homma, Y. and Fukuda, M. (2020) A comprehensive analysis of Rab GTPases reveals a role for Rab34 in serum starvation-induced primary ciliogenesis. J. Biol. Chem. 295, 12674-12685 Homma, Y., Kinoshita, R., Kuchitsu, Y., Wawro, P. S., Marubashi, S., Oguchi, M. E., Ishida, M., Fujita, N. and Fukuda, M. (2019) Comprehensive knockout analysis of the Rab family GTPases in epithelial cells. J. Cell Biol. 218, 2035-2050 Etoh, K. and Fukuda, M. (2019) Rab10 regulates tubular endosome formation through KIF13A and KIF13B motors. J. Cell Sci. 132, jcs226977 Kuchitsu, Y., Homma, Y., Fujita, N. and Fukuda, M. (2018) Rab7 knockout unveils regulated autolysosome maturation induced by glutamine starvation. J. Cell Sci. 131, jcs215442 Fujita, N., Huang, W., Lin, T.-H., Groulx, J.-F., Jean, S., Nguyen, J., Kuchitsu, Y., Koyama-Honda, I., Mizushima, N., Fukuda, M. and Kiger, A. A. (2017) Genetic screen in Drosophila muscle identifies autophagy-mediated T-tubule remodeling and a Rab2 role in autophagy. eLife 6, e23367 Homma, Y. and Fukuda, M. (2016) Rabin8 regulates neurite outgrowth in both GEF-activity-dependent and -independent manners. Mol. Biol. Cell 27, 2107-2118 Mrozowska, P. S. and Fukuda, M. (2016) Regulation of podocalyxin trafficking by Rab small GTPases in 2D and 3D epithelial cell cultures. J. Cell Biol. 213, 355-369 Marubashi, S., Shimada, H., Fukuda, M. & Ohbayashi, N. (2016) RUTBC1 functions as a GTPase-activating protein for Rab32/38 and regulates melanogenic enzyme trafficking in melanocytes. J. Biol. Chem. 291, 1427-1440 Hirano, S., Uemura, T., Annoh, H., Fujita, N., Waguri, S., Itoh, T. & Fukuda, M. (2016) Differing susceptibility to autophagic degradation activity of two LC3-binding proteins: SQSTM1/p62 and TBC1D25/OATL1. Autophagy 12, 312-326 Aizawa, M. & Fukuda, M. (2015) Small GTPase Rab2B and its specific binding protein Golgi-associated Rab2B interactor-like 4 (GARI-L4) regulate Golgi morphology. J. Biol. Chem. 290, 22250-22261 Etoh, K. &  Fukuda, M. (2015) Structure-function analyses of the small GTPase Rab35 and its efffector protein centaurin-β2/ACAP2 during neurite outgrowth of PC12 cells. J. Biol. Chem. 290, 9064-9074 Yatsu, A., Shimada, H., Ohbayashi, N. & Fukuda, M. (2015) Rab40C is a novel Varp-binding protein that promotes proteasomal degradation of Varp in melanocytes. Biol. Open  4, 267-275 Ishida, M., Ohbayashi, N. & Fukuda, M. (2015) Rab1A regulates anterograde melanosome transport by recruiting kinesin-1 to melanosomes through interaction with SKIP. Sci. Rep. 5, 8238 Yasuda, T. & Fukuda, M. (2014) Slp2-a controls renal epithelial cell size through regulation of Rap–ezrin signaling independently of Rab27. J. Cell Sci.127, 557-570 Matsui, T. & Fukuda, M. (2013) Rab12 regulates mTORC1 activity and autophagy through controlling the degradation of amino-acid transporter PAT4. EMBO Rep. 14, 450-457  Yatsu, A., Ohbayashi, N., Tamura, K. & Fukuda, M. (2013) Syntaxin-3 is required for melanosomal localization of Tyrp1 in melanocytes. J. Invest. Dermatol. 133, 2237-2246  Kobayashi, H. & Fukuda, M. (2013) Rab35 establishes the EHD1-association site by coordinating two distinct effectors during neurite outgrowth. J. Cell Sci. 126, 2424-2435 Yasuda, T., Saegusa, C., Kamakura, S., Sumimoto, H. & Fukuda, M. (2012) Rab27 effector Slp2-a transports the apical signaling molecule podocalyxin to the apical surface of MDCK II cells and regulates claudin-2 expression. Mol. Biol. Cell 23, 3229-3239 Ishida, M., Ohbayashi, N., Maruta, Y., Ebata, Y. & Fukuda, M. (2012) Functional involvement of Rab1A in microtubule-dependent anterograde melanosome transport in melanocytes. J. Cell Sci. 125, 5177-5187  Kobayashi, H. & Fukuda, M. (2012) Rab35 regulates Arf6 activity through centaurin-β2 (ACAP2) during neurite outgrowth. J. Cell Sci. 125, 2235-2243 Ohbayashi, N., Maruta, Y., Ishida, M. & Fukuda, M. (2012) Melanoregulin regulates retrograde melanosome transport through interaction with the RILP－p150Glued complex in melanocytes. J. Cell Sci. 125, 1508-1518 Mori, Y., Matsui, T., Furutani, Y., Yoshihara, Y. & Fukuda, M. (2012) Small GTPase Rab17 regulates dendritic morphogenesis and postsynaptic development of ippocampal neurons. J. Biol. Chem. 287, 8963-8973 Matsui, T., Itoh, T. & Fukuda, M. (2011) Small GTPase Rab12 regulates constitutive degradation of transferrin receptor. Traffic 12, 1432-1443  Itoh, T., Kanno, E., Uemura, T., Waguri, S. & Fukuda, M. (2011) OATL1, a novel autophagosome-resident Rab33B-GAP, regulates autophagosomal maturation. J. Cell Biol. 192, 839-853   Tamura, K., Ohbayashi, N., Ishibashi, K. & Fukuda, M. (2011) Structure-function analysis of VPS9-ankyrin-repeat protein (Varp) in the trafficking of tyrosinase-related protein 1 in melanocytes. J. Biol. Chem. 286, 7507-7521  Kanno, E., Ishibashi, K., Kobayashi, H., Matsui, T., Ohbayashi, N. & Fukuda, M. (2010) Comprehensive screening for novel Rab-binding proteins by GST pull-down assay using 60 different mammalian Rabs. Traffic 11, 491-507  Tamura, K., Ohbayashi, N., Maruta, Y., Kanno, E., Itoh, T. & Fukuda, M. (2009) Varp is a novel Rab32/38-binding protein that regulates Tyrp1 trafficking in melanocytes. Mol. Biol. Cell 20, 2900-2908  Fukuda, M., Kanno, E., Ishibashi, K. & Itoh, T. (2008) Large scale screening for novel Rab effectors reveals unexpected broad Rab binding specificity. Mol. Cell. Proteomics 7, 1031-1042  Itoh, T., Fujita, N., Kanno, E., Yamamoto, A., Yoshimori, T. & Fukuda, M. (2008) Golgi-resident small GTPase Rab33B interacts with Atg16L and modulates autophagosome formation. Mol. Biol. Cell 19, 2916-2925  Yu, E., Kanno, E., Choi, S., Sugimori, M., Moreira, J. E., Llinas, R. R. & Fukuda, M. (2008) Role of Rab27 in synaptic transmission at the squid giant synapse. Proc. Natl. Acad. Sci. USA 105, 16003-16008 Please see http://www.ac.cyberhome.ne.jp/~fukuda/top_page.htm for other publications. Activities in Academic Societies Japanese Biochemical Society, Molecular Biology Society of Japan, Japan Society for Cell Biology, Japan Neuroscience Society, Japanese Society for Pigment Cell Research, American Society for Biochemistry and Molecular Biology, American Society for Cell Biology Teaching Life Science A-C (General Education), Molecular cell biology I (Undergraduate), Advanced Cell Biology I-IV (Graduate School), etc. Recent Activities Our bodies are made up of several tens of trillions of cells, which individually are considered to be the fundamental units of life. Various small organs, covered in membranes and called organelles, exist inside cells. Although these organelles possess unique functions, they do not exist independently of each other, but rather frequently exchange information by transport of membrane-wrapped substances (generally called membrane trafficking). Because defects in appropriate membrane trafficking causes a variety of human diseases, understanding the molecular mechanisms behind membrane trafficking is an important research challenge in biology and medical science. The existence of “traffic controllers” is important for the regulation of membrane trafficking, and in our laboratory we focus on the Rab protein, which acts as a traffic controller, to understand the molecular mechanisms underlying membrane trafficking. Although various kinds of membrane trafficking occur inside cells, in our laboratory we are particularly interested in autophagy, neuron-specific membrane trafficking such as the release of neurotransmitters, in addition to melanosome transport in melanocytes; and we are engaged in revealing the molecular mechanisms behind them. Message to Students Biology remains an academic field, which is not fully established. Although our understanding of the molecular mechanisms behind biological phenomena has grown by leaps and bounds in recent years due to the development of molecular biology, there still remains a mountain of information that we have not yet discovered. In other words, there are enormous opportunities for young people aspiring to engage in life sciences research in the future. Why not explore the mysteries of life together with us? ResearchLaboratories Department of Integrative Life Sciences Department of Ecological Developmental Adaptability Life Sciences Department of Molecular and Chemical Life SciencesResearchAward GO TOP Graduate School of Life SciencesTohoku University 2-1-1 Katahira, Aoba-Ku, Sendai 980-8577 Academic Affairs Section Tel : +81-22-217-5706 / Fax: +81-22-217-5704   General Affairs Section Tel : +81-22-217-5702 / Fax: +81-22-217-5704   Contact ・Privacy Policy HOMEAbout UsAbout UsMessage from the DeanOrganizationMovieResearchLaboratories Department of Integrative Life Sciences Department of Ecological Developmental Adaptability Life Sciences Department of Molecular and Chemical Life SciencesResearchAwardEducationDegree ProgramsCourseSyllabusScheduleStudent LifeAdmissionAdmission InformationApplicationExamination Schedule and Application GuidelinesInformation Session(2024)Admission and Tuition FeesAdmission PolicyVoices from Graduates and Current StudentsAdmissions Q&AInquiries about Entrance ExaminationsFinancial SupportFor StudentsGraduate School&＃039;s Message Board for Students Information about Completion and Advancement to the Doctoral Course ProceduresCertificatesAbout Issuance of Various CertificatesNotice Regarding the Suspension of Operation of the Automatic Certificate Issuing MachinesLeave of absence/withdrawal from universityCampus Life, Various consultation servicesContactAccessLinkSitemapInformationAdmissionResearchAwardSeminarJobNewsAnnouncementOther © 2004-2023 Graduate School of Life Sciences, Tohoku University no cache